Endocrine Abstracts

Introduction: Gestational diabetes (GD) is frequently associated with obesity and family history of diabetes. Besides these, other risks factors have been proposed, as previous GD, macrosomy or abnormal reproductive history.Methods: We conducted a retrospective comparative study including all patients diagnosed of GD during 1999 and 2008. The analyzed variables were incidence and risk factors of GD.Results: We included 384 patients...

Background: Patients with diabetes insipidus (DI) that suffer of adipsia usually are difficult to treat, and requiring close monitorization.Aim: To know long-term outcome of patients with DI associated to adipsia.Subjects: From January 1989 to December 2006 were attended five patients (two males) with DI plus adipsia, aged 32±14.64 years, range 10–51. Being the aetiology X histiocytosis, craneapharyngioma, suprasellar men...

Background: Classic 21-hydroxylase deficiency, due to severe mutations in CYP21B gene, is an uncommon disease (1/ 150 000). Salt-wasting form accounts for 75% of the cases and turns up with gluco- and mineralocorticoid deficiency as well as feminine hermaphroditism. Although wide psycho-social repercussion especially in women is known, the rarity of the disease and losses in follow-up may lead to a scarce clinical experience. We present 3 adult patients with CAH- SW followed r...

Despite advances in the management of last years, diabetes and its complications are still the most frequent cause of admission in Endocrine Departments. Nowadays, in our Hospital, 60% of admissions are due to Diabetes, and more than a half of these are diabetic ketoacidosis (DKA) (35.4%).Objective: Analize DKA episodes in our medical area in the last 12 years and compare them divided in two periods.Methods: Divide DKA episodes in ...

Background: Nonclassic congenital adrenal hyperplasia (NC-CAH) caused by mutations in CYP21B gene is an inherited disorder with various clinical forms in relation to the 21-hydroxylase (21OH) activity. Classic forms are recognized early during neonatal period as salt-wasting crisis or genital ambiguity, while non-classic form presents later with wide hyperandrogenic spectrum. Genetic testing has proved to be the definitive diagnostic method.Aim: To obser...